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Image Search Results
Journal: Human Molecular Genetics
Article Title: Atp13a2-deficient mice exhibit neuronal ceroid lipofuscinosis, limited α-synuclein accumulation and age-dependent sensorimotor deficits
doi: 10.1093/hmg/ddt057
Figure Lengend Snippet: Tyrosine hydroxylase immunostaining and stereological analysis. TH immunostaining of representative mid-brain sections showing dopaminergic neurons in the SNc of Atp13a2+/+ (A) and Atp13a2−/− (B) mice at 27 months of age; sections were counterstained with cresyl violet; ×100 magnification. (C) Average number of tyrosine hydroxylase-positive neurons in the SNc of Atp13a2+/+ and Atp13a2−/− mice at 22–27 months of age and (D) volume of SNc in the same mice, as determined by stereological analysis. n = 6 mice of each genotype for all analyses. The values shown are means ± SEM.
Article Snippet:
Techniques: Immunostaining